… “Here we showed that 222 nm is essentially equi-effective at killing antibiotic-resistant bacteria as conventional germicidal UV lamps (254 nm). However, compared to the latter, 222-nm light does not induce typical UV-associated premutagenic DNA lesions in human keratinocytes in a 3D human skin model and appears to be safe for skin of exposed hairless mice, as assessed by eight cellular and molecular endpoints associated with damaged skin.” …… “Other potential applications of far-UVC light is sterilization of any environment with a high likelihood of airborne-based pathogen transmission, including tuberculosis, small pox, severe acute respiratory syndrome (SARS) and pandemic influenza, which collectively affects one billion people annually (47). Although upper-room UV-irradiation systems based on conventional broad-spectrum UV lamps (48) have long been considered for room sterilization (49–51), they cannot be widely used due to safety concerns relating to skin cancer and cataract risks (49, 52, 53).Collectively, our studies suggest that far-UVC light (200–225 nm), unlike conventional UV germicidal lamps, has considerable promise to be a safe and inexpensive modality for SSI reduction, while being cytotoxic to both drug-resistant and drug-sensitive microbes (22).” …